Thymosin Alpha-1 Peptide

Thymosin Alpha-1 is the N-terminally acetylated, fully synthetic version of prothymosin α fragment 1–28 originally isolated from thymosin fraction 5 (TF5). For Research Use Only. Not for human use. This research-grade lyophilized peptide is produced under strict quality controls and provided with full analytical documentation, making it a reference compound for immunology, virology, and oncology research. According to published scientific literature, Thymosin Alpha-1 (thymalfasin) has been studied extensively as an immunomodulatory peptide; it has received regulatory approval in over 35 countries and has been granted FDA orphan drug designation for hepatocellular carcinoma and stage IV melanoma (fda.gov). It remains unapproved by the FDA and EMA for general therapeutic use in the United States and the European Union.

Key Scientific Attributes

• High-purity Thymosin Alpha-1 (≥ 99% by HPLC/MS, acetate salt form)
• Verified 28-amino-acid sequence with correct N-terminal acetylation
• Lyophilized formulation for maximum long-term stability
• Full Certificate of Analysis (COA) with HPLC, MS, and amino acid analysis
• Manufactured in GMP-aligned, ISO-compliant facilities
• Suitable for T-cell/NK activation, TLR signaling, and antiviral immunity studies

Research-Referenced Attributes (Based on published scientific literature; not therapeutic claims. For research use only.)

• Studied for roles in T-cell maturation and Th1 cytokine modulation (IL-2, IFN-γ) in in vitro and preclinical models (pmc.ncbi.nlm.nih.gov)
• Investigated in NK cell cytotoxicity and dendritic cell antigen presentation research
• Subject of published literature on TLR2/TLR9 agonism and Th1-polarized immune signaling
• Investigated in published studies across chronic viral infection models, immuno-oncology, vaccine adjuvancy, and critical illness research contexts (mdpi.com)

Why Researchers Choose Nationwide Peptides Thymosin Alpha-1

• An exact published reference sequence with correct N-terminal acetylation
• Transparent analytical data (HPLC >99%, MS confirmation of acetylation)
• Trusted by immunology, virology, and critical care laboratories
• Competitive research pricing with bulk options

For Research Use Only. Not for human or animal use. Not intended to diagnose, treat, cure, or prevent any disease or condition.