AICAR Peptide

For Research Use Only. Not for human use.

AICAR (Acadesine, AICA-riboside) is an adenosine analog that enters cells and is phosphorylated to ZMP, mimicking AMP and directly activating AMPK — the master metabolic sensor. First studied in the 1990s for cardiac ischemia research, AICAR has become the gold-standard pharmacological tool for AMPK pathway investigation. Currently under clinical investigation for B-cell chronic lymphocytic leukemia (under orphan designation), it remains a widely used reference compound in metabolic and oncology research. This research-grade lyophilized powder is synthesized under strict quality controls and provided with full analytical documentation. For laboratory research use only.

Key Scientific Attributes

• High-purity AICAR (≥ 99% by HPLC/MS, free base or salt form)
• Verified structure: 5-Amino-1-β-D-ribofuranosyl-imidazole-4-carboxamide
• Lyophilized formulation for maximum long-term stability
• Full Certificate of Analysis (COA) with HPLC, MS, NMR, and endotoxin testing
• Manufactured in GMP-aligned, ISO-compliant facilities
• Utilized in AMPK phosphorylation, PGC-1α induction, and metabolic reprogramming studies

Research-Referenced Attributes (Based on scientific literature; not intended as therapeutic claims. For research use only.)

• Direct, allosteric AMPK activation observed in in vitro and in vivo research models
• Investigated in studies of mitochondrial biogenesis and fatty acid oxidation via PGC-1α in muscle cell models — see pmc.ncbi.nlm.nih.gov
• Studied in ischemia research models and cardioprotection investigations
• Investigated for potential anti-proliferative effects through mTOR inhibition and autophagy induction in cancer cell research
• Widely used as a reference AMPK activator in peer-reviewed metabolic and oncology research

Why Researchers Choose AICAR Peptide

• Pharmaceutical-grade purity consistent with published research standards
• Transparent analytical data (HPLC ≥99%, MS/NMR confirmation)
• Trusted by metabolism and oncology research laboratories
• Competitive research pricing with bulk options available

This product is intended solely for in vitro and laboratory research purposes. It is not approved for human or animal use, is not a drug or dietary supplement, and is not intended to diagnose, treat, cure, or prevent any disease or condition.